Frameskin Wrap is waterproof and oil resistant and will stay in position until you take it off. Moisture and grit can't get behind Frameskin Wrap like it does with neoprene protectors and when it comes time to removal, it will leave no sticky residue behind.
1 roll is more than enough for a thick wrap for a mountain bike chainstay.
There's many other uses. You can use Frameskin Wrap to protect your crank arm from the nasties of the DH shuttle trailer, you can tape off bar tape, wrap a little on your handlebars where you zip-tie your race plates. You can even cinch cables closer to the frame so they don't rub your legs, repair a torn sidewall or to lash a stick to your seatpost should your seat clamp break so you can get home (yes, we did this). Keep a roll in your pack for emergencies.
Clean the surface of your driveside chain and seat stays. Remove the backing liner from the roll in lengths of about 150mm to 200mm at a time. Snip a little off the sides on the free end of the tape to make a wedge shape to make it easier to pin down to the frame with your thumb. Place the end onto your frame and stretch and wrap it around (over and under the stay) creating an overlap of 1/2 to 2/3. Stretching and overlapping the wrap activates the self fusing properties of the tape. Repeat this 'stretch and wrap' action until you get to the end of the roll and then press your thumb firmly on the end to bond it to the wrap beneath. Install complete. Ride bike. Smile.